Table 2.

Defensive effect of PELE on tissue proteins, GSH, TBARS, nitrite and H₂O₂ contents in lungs of rat

Treatment	Protein (μg/mg tissue)	GSH (nmole/min/mg protein)	TBARS (nmole/mg protein)	Nitrite (μM/mL)	H2O2 (nmole/mg tissue)
Control	2.5 ± 0.4a	22.0 ± 1.5a	3.1 ± 0.3f	34.5 ± 2.5f	1.03 ± 0.1f
Vehicle	2.4 ± 0.6a	21.6 ± 2.6a	3.9 ± 0.8e	39.4 ± 2.0e	1.25 ± 0.3e
CCl4 (1 mL/kg)	0.4 ± 0.5d	8.5 ± 2.2d	6.9 ± 1.1a	59.2 ± 2.5a	3.43 ± 0.3a
CCl4 + silymarin	2.2 ± 0.3ab	19.7 ± 2.4b	4.6 ± 0.4b	43.2 ± 1.2c	2.30 ± 0.4b
CCl4 + PELE (200 mg/kg) bw)	1.2 ± 0.16c	15.8 ± 1.2c	4.4 ± 0.9bc	45.0 ± 1.6b	2.17 ± 0.5c
CCl4 + PELE (400 mg/kg) bw)	2.1 ± 0.8b	19.7 ± 1.5b	4.1 ± 0.6de	41.6 ± 2.1d	1.95 ± 0.2d
PELE (400 mg/kg)	2.3 ± 0.7ab	20.9 ± 1.5ab	4.2 ± 0.5cd	42.1 ± 1.0cd	2.06 ± 0.3cd

Mean ± SD (n = 6), ^a-f (Means with different superscript letters) specify significance at P < 0.01, PELE; methanolic extract of P. emblica leaves