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. 2016 Oct 25;16:600. doi: 10.1186/s12879-016-1932-1

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Phylogenetic trees of HA (a) and NA (b) genes of AIV H5N6 and reference isolates. It demonstrated that AIV H5N6 isolates obtained from both human and poultry in China were very heterogeneous. Sequences labeled with red circles are current human infected isolates of AIV H5N6, with red triangles are the sequences of probable ancestors based on the current study, and with blue triangles are sequences of probable ancestors based on opinions from other researchers