Table 2. Characteristics of patients who had a posttreatment neck dissection.
| Characteristic | p16 positive (n=69) | p16 negative (n=30) | P |
|---|---|---|---|
| Assigned treatment | .39* | ||
| SFX + cisplatin | 39 (56.5) | 14 (46.7) | |
| AFX-C + cisplatin | 30 (43.5) | 16 (53.3) | |
| Age (y) | .93† | ||
| Median (range) | 55 (38-66) | 55 (37-71) | |
| Sex | 1.00* | ||
| Male | 63 (91.3) | 27 (90.0) | |
| Female | 6 (8.7) | 3 (10.0) | |
| Race | .06* | ||
| White | 62 (89.9) | 22 (73.3) | |
| Non-white | 7 (10.1) | 8 (26.7) | |
| Zubrod performance status | .36* | ||
| 0 | 47 (68.1) | 17 (56.7) | |
| 1 | 22 (31.9) | 13 (43.3) | |
| Smoking history: pack-years‡ | (n=59) | (n=22) | <.001† |
| Median (range) | 10.8 (0-152) | 38.5 (0-100) | |
| Primary site | .40* | ||
| Oropharynx, NOS | 10 (14.5) | 5 (16.7) | |
| Tonsillar fossa, tonsil | 30 (43.5) | 14 (46.7) | |
| Base of tongue | 28 (40.6) | 9 (30.0) | |
| Pharyngeal oropharynx | 1 (1.4) | 1 (3.3) | |
| Soft palate | 0 (0.0) | 1 (3.3) | |
| T stage | .08† | ||
| T2 | 31 (44.9) | 9 (30.0) | |
| T3 | 22 (31.9) | 9 (30.0) | |
| T4 | 16 (23.2) | 12 (40.0) | |
| N stage | .71† | ||
| N1 | 2 (2.9) | 2 (6.7) | |
| N2a | 15 (21.7) | 6 (20.0) | |
| N2b | 26 (37.7) | 7 (23.3) | |
| N2c | 12 (17.4) | 9 (30.0) | |
| N3 | 14 (20.3) | 6 (20.0) | |
| Primary disease status before neck dissection | .09§ | ||
| Persistent abnormality | 9 (13.0) | 4 (13.3) | |
| No disease (cCR) | 50 (72.5) | 16 (53.3) | |
| Unknown/no assessment | 10 (14.5) | 10 (33.3) | |
| Neck disease status prior to neck dissection | .42§ | ||
| Persistent abnormality | 38 (55.1) | 13 (43.3) | |
| No disease (cCR) | 18 (26.1) | 8 (26.7) | |
| Unknown/no assessment | 13 (18.8) | 9 (30.0) | |
| Interval between chemoRT and neck dissection (d) | .95† | ||
| Median (range) | 71 (17-154) | 67 (35-169) |
Abbreviation: cCR = clinical complete response. Other abbreviations as in Table 1.
Values are number (percentage) unless otherwise noted.
*
Fisher exact test. Primary site is tested as tonsil or base of tongue versus others.
†
Wilcoxon rank-sum test.
‡
A pack-year is defined as the equivalent of smoking one pack of cigarettes a day for 1 year.
§
Chi-squared test.