Table 4. Two-year endpoints by p16 status and neck treatment after chemoradiation.
2-y Estimates (%) | ||||
---|---|---|---|---|
| ||||
Parameter | Patients (n) | LRF | PFS | OS |
p16 positive | ||||
No neck dissection | 130 | 11.2 (6.4-17.5) | 75.3 (67.9-82.8) | 86.9 (81.1-92.7) |
Neck dissection with pCR | 54 | 7.5 (2.4-16.7) | 85.2 (75.7-94.7) | 92.6 (85.6-99.6) |
Neck dissection without pCR | 15 | 20.0 (4.5-43.3) | 73.3 (51.0-95.7) | 86.7 (69.5-100.0) |
Neck dissection with/without pCR | 69 | 10.2 (4.5-18.8) | 82.6 (73.7-91.6) | 91.3 (84.7-98.0) |
p16 negative | ||||
No neck dissection | 63 | 31.1 (19.9-43.0) | 47.6 (35.3-60.0) | 57.1 (44.9-69.4) |
Neck dissection with pCR | 16 | 26.0 (7.5-49.6) | 50.0 (25.5-74.5) | 62.5 (38.8-86.2) |
Neck dissection without pCR | 14 | 75.0 (36.0-92.2) | 14.3 (0.0-32.6) | 50.0 (23.8-76.2) |
Neck dissection with/without pCR | 30 | 49.1 (29.2-66.3) | 33.3 (16.5-50.2) | 56.7 (38.9-74.4) |
Abbreviations as in Table 3.