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. 2016 Sep 16;5(9):e003262. doi: 10.1161/JAHA.116.003262

Table 3.

Intertrajectory Differences in Probability of Elevated hs‐CRP (2–10 mg/L)

Strata Trajectory Trajectory Name N Predicted Probability CRP >2 (95% CI) Overall P Valuea Group Differencesb Interaction P Valuec
Men, y
18 to <30 1 Initial weight loss 81 0.07 (0.04–0.15) 0.001 3 4 0.83
2 Stable, low weight 545 0.11 (0.08–0.15) 3 4
3 Steep weight gain 251 0.18 (0.13–0.25) 1 2
4 Steepest weight gain 41 0.25 (0.14–0.42) 1 2
30 to <40 1 Initial weight loss 47 0.15 (0.07–0.28) 0.30 No group differences observed 0.18
3 Stable low weight 307 0.17 (0.12–0.23)
2 Stable weight gain 363 0.17 (0.12–0.23)
4 Steep weight gain 120 0.23 (0.15–0.33)
5 Steepest weight gain 15 0.35 (0.15–0.63)
40 to 66 1 Initial weight loss 27 0.19 (0.08–0.37) 0.71 No group differences observed 0.66
2 Stable low weight 259 0.19 (0.14–0.26)
3 Stable weight gain 390 0.18 (0.13–0.23)
4 Steep weight gain 137 0.22 (0.15–0.30)
5 Steepest weight gain 36 0.25 (0.13–0.42)
Women, y
18 to <30 1 Weight loss 87 0.03 (0.01–0.09) <0.0001 2 3 4 5 6 0.43
2 Maintenance 322 0.12 (0.08–0.17) 1 4 6
3 Stable weight gain 344 0.14 (0.10–0.19) 1 6
5 Weight gain and loss 43 0.13 (0.05–0.28) 1 6
4 Steep weight gain 121 0.20 (0.13–0.30) 1 2 6
6 Steepest weight gain 18 0.78 (0.53–0.92) 1 2 3 4 5
30 to <40 1 Weight loss 24 0.18 (0.07–0.37) 0.006 0.10
2 Maintenance 153 0.11 (0.07–0.17) 4 6
3 Stable weight gain 520 0.16 (0.12–0.19) 4 6
4 Steep weight gain 311 0.23 (0.18–0.29) 2 3
6 Steepest weight gain 39 0.32 (0.19–0.50) 2 3
5 Weight gain and loss 22 0.16 (0.05–0.40)
40 to 66 1 Weight loss 38 0.21 (0.12–0.36) 0.0002 4 0.29
2 Maintenance 439 0.19 (0.15–0.23) 3 4
3 Stable weight gain 374 0.27 (0.23–0.32) 2 4
4 Steepest weight gain 44 0.48 (0.33–0.63) 1 2 3
a

Overall test of trajectory significance in full models adjusted for baseline weight (quadratic), height (averaged across repeated measures), smoker status (ever/never) and current number of cigarettes (both for men only), and a random intercept for community.

b

Numbers indicate groups that were significantly different in pairwise comparison tests. For example, for men aged 18 to 30, group 1 differed significantly from groups 3 and 4.

c

Likelihood ratio test for interaction effects between baseline weight (measured linearly).