Table 1.
Baseline Characteristicsa of Study Population by Family History of Premature CHD Status: The ARIC Study (1987–1989)
| No FHx of Premature CHD (9006) | FHx of Premature CHD (990) | Overall (9996) | P‐Value | |
|---|---|---|---|---|
| AHA‐defined PA categories, N (%) | 0.913 | |||
| Recommended | 3612 (40.1) | 404 (40.8) | 4016 (40.2) | |
| Intermediate | 2329 (25.9) | 253 (25.6) | 2582 (25.8) | |
| Poor | 3065 (34.0) | 333 (33.6) | 3398 (34.0) | |
| PA levels (METs×min/week [continuous])b | 408.6 (0.0, 1008.9) | 423.4 (0.0, 995.0) | 414.0 (0.0, 1006.8) | 0.852 |
| Age, y | 53.9±5.7 | 53.1±5.5 | 53.8±5.7 | <0.001 |
| BMI, kg/m2 | 27.3±5.0 | 27.4±5.2 | 27.3±5.0 | 0.679 |
| Male, N (%) | 3993 (44.3) | 396 (40.0) | 4389 (43.9) | 0.009 |
| Race/center, N (%) | <0.001 | |||
| Minneapolis, MN whites | 2597 (28.8) | 269 (27.2) | 2866 (28.7) | |
| Washington County, MD Whites | 2372 (26.3) | 327 (33.0) | 2699 (27.0) | |
| Forsyth County, NC Whites | 2158 (24.0) | 289 (29.2) | 2447 (24.5) | |
| Forsyth County, NC blacks | 227 (2.5) | 11 (1.1) | 238 (2.4) | |
| Jackson, MS blacks | 1652 (18.3) | 94 (9.5) | 1746 (17.5) | |
| Education, N (%) | 0.991 | |||
| <High School | 1614 (17.9) | 176 (17.8) | 1790 (17.9) | |
| High School or Vocational School | 3808 (42.3) | 419 (42.3) | 4227 (42.3) | |
| College, Graduate, or Professional School (%) | 3575 (39.7) | 395 (39.9) | 3970 (39.8) | |
| Smoking status, N (%) | 0.060 | |||
| Never | 4107 (45.6) | 418 (42.3) | 4525 (45.3) | |
| Former | 2882 (32.0) | 321 (32.5) | 3203 (32.1) | |
| Current | 2013 (22.4) | 250 (25.3) | 2263 (22.7) | |
| Current alcohol consumption, N (%) | 5364 (59.7) | 602 (61.0) | 5966 (59.9) | 0.446 |
| Total cholesterol, mg/dL | 213.5±41.0 | 219.3±40.8 | 214.1±41.0 | <0.001 |
| HDL, mg/dL | 52.5±17.0 | 51.6±16.0 | 52.4±16.9 | 0.124 |
| LDL, mg/dL | 136.2±38.2 | 141.0±37.8 | 136.6±38.1 | <0.001 |
| Triglycerides, mg/dL | 126.7±84.6 | 135.1±78.9 | 127.5±84.1 | 0.003 |
| Diabetes mellitus N (%) | 773 (8.6) | 92 (9.3) | 865 (8.7) | 0.485 |
| Systolic BP, mm Hg | 119.5±17.4 | 119.9±17.3 | 119.5±17.4 | 0.463 |
| Hypertension, N (%) | 2553 (28.4) | 304 (31.0) | 2857 (28.7) | 0.094 |
| Estimated GFR, mL/min per 1.73 m2, N (%) | 0.028 | |||
| ≥90 | 7543 (84.2) | 860 (87.2) | 8403 (84.5) | |
| 60 to <90 | 1344 (15.0) | 117 (11.9) | 1461 (14.7) | |
| <60 | 68 (0.8) | 9 (0.9) | 77 (0.8) |
AHA indicates American Heart Association; ARIC, Atherosclerosis Risk in Communities; BMI, body mass index; BP, blood pressure; CHD, coronary heart disease; FHx, family history; GFR, glomerular filtration rate; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; METS, metabolic equivalents of task; PA, physical activity.
a
Data are means (SDs) or number (%).
b
Median (interquartile interval).