Table 2.
Association of Family History of Premature CHD Status With Baseline AHA‐Defined Physical Activity Categories (Odds Ratios, 95% CI) at ARIC Visit 1 (1987–1989) and With Change in Physical Activity Levels (METS×min/week) From ARIC Visit 1 to Visit 3 (1987–1995)
| Model 1a | Model 2b | Model 3c | |
|---|---|---|---|
| Intermediate compared with poord | |||
| No FHx | Reference (1) | Reference (1) | Reference (1) |
| FHx | 0.91 (0.77, 1.09) | 0.94 (0.79, 1.12) | 0.98 (0.82, 1.18) |
| Recommended compared with poord | |||
| No FHx | Reference (1) | Reference (1) | Reference (1) |
| FHx | 0.93 (0.80, 1.09) | 0.97 (0.83, 1.14) | 1.01 (0.86, 1.20) |
| Change of PA from visit 1 to visit 3 | −0.11 (−0.30, 0.08) | −0.06 (−0.24, 0.13) | −0.01 (−0.20, 0.18) |
AHA indicates American Heart Association; ARIC, Atherosclerosis Risk in Communities; ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index; CHD, coronary heart disease; FHx, family history; GFR, glomerular filtration rate; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; METS, metabolic equivalents of task; PA, physical activity.
Model 1: Age, sex, race/center.
Model 2: Model 1+education, BMI, smoking status, and alcohol intake.
Model 3: Model 2+additional potential mediating variables (of the association between PA and ASCVD risk)−systolic blood pressure, antihypertensive medication use, diabetes, LDL cholesterol, HDL cholesterol, triglycerides, use of lipid‐lowering medications, and estimated GFR.
Multivariable‐adjusted multinomial regression.