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. 2016 Aug 29;5(9):e003741. doi: 10.1161/JAHA.116.003741

Table 2.

CVD and All‐Cause Mortality Hazard Ratios (95% CI) for Self‐Rated Health and Nontraditional Biomarkers

Variablea Model 1 Model 2
HR 95% CI P Value HR 95% CI P Value
CVD mortality (N=4033)
Self‐rated health 1.92 1.51 to 2.45 <0.001 1.84 1.45 to 2.35 <0.001
Log CRP 1.22 0.97 to 1.52 0.086 1.17 0.92 to 1.50 0.189
Urinary albumin 1.22 1.12 to 1.32 <0.001 1.20 1.11 to 1.30 <0.001
Triglycerides 1.16 1.06 to 1.27 0.002 1.10 1.00 to 1.21 0.056
Uric acid 1.10 0.84 to 1.44 0.475 1.08 0.84 to 1.39 0.522
Fibrinogen 1.52 1.26 to 1.82 <0.001 1.48 1.22 to 1.81 <0.001
All‐cause mortality (N=4677)
Self‐rated health 1.58 1.43 to 1.75 <0.001 1.54 1.38 to 1.71 <0.001
Log CRP 1.19 1.09 to 1.30 <0.001 1.15 1.06 to 1.26 0.003
Urinary albumin 1.13 1.07 to 1.19 <0.001 1.11 1.05 to 1.17 0.001
Triglycerides 1.13 1.06 to 1.21 0.001 1.08 1.02 to 1.15 0.017
Uric acid 1.11 1.00 to 1.22 0.045 1.10 1.00 to 1.22 0.049
Fibrinogen 1.19 1.08 to 1.30 0.001 1.16 1.06 to 1.28 0.003

Both models stratify on 5‐year age cohort, sex, and education. Model 1 includes race/ethnicity and chronic disease as covariates; model 2 also includes 10‐year atherosclerotic cardiovascular disease risk. Each hazard ratio reflects a 1‐SD change in the predictor. CRP indicates C‐reactive protein; CVD, cardiovascular disease.

a

Standardized mean=0, standard deviation=1.0.