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. 2016 Sep 23;5(9):e003887. doi: 10.1161/JAHA.116.003887

Table 3.

Arterial and Ventricular Properties in Fontan and Control Patients

All Fontan SRV SLV Controls
n 170 57 113 170
Heart rate, bpm 74±15a 74±15a 74±15a 70±11
Vascular properties
Systolic blood pressure, mm Hg 110±15a 109±14a 110±15a 115±14
Pulse pressure, mm Hg 43±12 43±12 43±12 44±9
Aortic compliance, mL/mm Hg 2.05±0.92 2.03±0.83 2.05±0.97 1.90±0.49
SVRI, dyne·s·cm−5·m2 2128±794 2020±548a 2184±892 2216±403
Effective arterial elastance (Ea), mm Hg/mL 1.35±0.55 1.30±0.39 1.38±0.61 1.33±0.30
Ventricular geometry
Ventricular end‐diastolic volume index, mL/m2 96±34a 101±26a 94±38a 73±13
Posterior wall thickness, mm 9.1±2.3a 8.6±2.1 9.3±2.3a 8.1±1.4
Ventricular mass index, g/m2 92±32a 91±28a 92±34a 69±15
Systolic function, VA coupling and efficiency
Ejection fraction, % 50±9a 48±8a, b 51±10a 63±5
Stroke volume index, mL/m2 47±15 48±13 46±16 45±7
Cardiac index, L/min per m2 3.35±1.01a 3.36±0.85a 3.34±1.09 3.16±0.49
End‐systolic elastance (Ees), mm Hg/mL 1.39±0.67a 1.19±0.41a, b 1.48±0.75a 2.37±0.63
Ees×mass, mm Hg·g/mL 215±115a 174±64a, b 229±125a 283±79
V0, mL −0.1±35 −1.0±31.9 0.3±37.2 2.4±11
VA coupling ratio, Ees/Ea 1.05±0.35a 0.97±0.34a, b 1.09±0.36a 1.80±0.34
PRSW, erg·cm−3·103 72±17a 70±18a 72±17a 91±14
Peak power index, mm Hg/s 320±94a 307±109a 326±86a 369±77
Mechanical efficiency (EW/PVA) 0.62±0.08a 0.60±0.09a, b 0.63±0.08a 0.74±0.04
Energetic efficiency, % 19.8±2.6a 19.4±2.8a 20.1±2.4a 23.4±1.2
Diastolic function
DWS 0.27±0.11a 0.23±0.12a, b 0.28±0.11a 0.39±0.07
E/A ratio (n with data) 1.50±0.67a (154) 1.46±0.65a (49) 1.52±0.68a (105) 1.88±0.54 (164)
Deceleration time, ms (n with data) 182±48 (146) 185±52 (47) 181±46 (99) 184±27 (161)
PV atrial velocity, m/s (n with data) 0.30±0.14a (90) 0.28±0.11a (26) 0.31±0.15a (64) 0.25±0.09 (151)
PV S/D flow velocity ratio (n with data) 0.84±0.54a (61) 0.91±0.66 (20) 0.81±0.48a (41) 0.98±0.35 (160)
IVRT, ms (n with data) 69±32a (92) 73±34a (29) 66±31a (63) 54±22 (170)

bpm indicates beats per minute; DWS, diastolic wall strain; IVRT, isovolumic relaxation time; PRSW, preload recruitable stroke work; PV, pulmonary vein; S/D, systolic/diastolic; SLV, single left ventricle; SRV, single right ventricle; SVRI, systemic vascular resistance index; VA coupling, ventricular‐arterial coupling; V0, ventricular volume axis intercept of end‐systolic pressure volume relationship.

a

P<0.05 versus controls.

b

P<0.05 SRV versus SLV.