Table 3.
All Fontan | SRV | SLV | Controls | |
---|---|---|---|---|
n | 170 | 57 | 113 | 170 |
Heart rate, bpm | 74±15a | 74±15a | 74±15a | 70±11 |
Vascular properties | ||||
Systolic blood pressure, mm Hg | 110±15a | 109±14a | 110±15a | 115±14 |
Pulse pressure, mm Hg | 43±12 | 43±12 | 43±12 | 44±9 |
Aortic compliance, mL/mm Hg | 2.05±0.92 | 2.03±0.83 | 2.05±0.97 | 1.90±0.49 |
SVRI, dyne·s·cm−5·m2 | 2128±794 | 2020±548a | 2184±892 | 2216±403 |
Effective arterial elastance (Ea), mm Hg/mL | 1.35±0.55 | 1.30±0.39 | 1.38±0.61 | 1.33±0.30 |
Ventricular geometry | ||||
Ventricular end‐diastolic volume index, mL/m2 | 96±34a | 101±26a | 94±38a | 73±13 |
Posterior wall thickness, mm | 9.1±2.3a | 8.6±2.1 | 9.3±2.3a | 8.1±1.4 |
Ventricular mass index, g/m2 | 92±32a | 91±28a | 92±34a | 69±15 |
Systolic function, VA coupling and efficiency | ||||
Ejection fraction, % | 50±9a | 48±8a, b | 51±10a | 63±5 |
Stroke volume index, mL/m2 | 47±15 | 48±13 | 46±16 | 45±7 |
Cardiac index, L/min per m2 | 3.35±1.01a | 3.36±0.85a | 3.34±1.09 | 3.16±0.49 |
End‐systolic elastance (Ees), mm Hg/mL | 1.39±0.67a | 1.19±0.41a, b | 1.48±0.75a | 2.37±0.63 |
Ees×mass, mm Hg·g/mL | 215±115a | 174±64a, b | 229±125a | 283±79 |
V0, mL | −0.1±35 | −1.0±31.9 | 0.3±37.2 | 2.4±11 |
VA coupling ratio, Ees/Ea | 1.05±0.35a | 0.97±0.34a, b | 1.09±0.36a | 1.80±0.34 |
PRSW, erg·cm−3·103 | 72±17a | 70±18a | 72±17a | 91±14 |
Peak power index, mm Hg/s | 320±94a | 307±109a | 326±86a | 369±77 |
Mechanical efficiency (EW/PVA) | 0.62±0.08a | 0.60±0.09a, b | 0.63±0.08a | 0.74±0.04 |
Energetic efficiency, % | 19.8±2.6a | 19.4±2.8a | 20.1±2.4a | 23.4±1.2 |
Diastolic function | ||||
DWS | 0.27±0.11a | 0.23±0.12a, b | 0.28±0.11a | 0.39±0.07 |
E/A ratio (n with data) | 1.50±0.67a (154) | 1.46±0.65a (49) | 1.52±0.68a (105) | 1.88±0.54 (164) |
Deceleration time, ms (n with data) | 182±48 (146) | 185±52 (47) | 181±46 (99) | 184±27 (161) |
PV atrial velocity, m/s (n with data) | 0.30±0.14a (90) | 0.28±0.11a (26) | 0.31±0.15a (64) | 0.25±0.09 (151) |
PV S/D flow velocity ratio (n with data) | 0.84±0.54a (61) | 0.91±0.66 (20) | 0.81±0.48a (41) | 0.98±0.35 (160) |
IVRT, ms (n with data) | 69±32a (92) | 73±34a (29) | 66±31a (63) | 54±22 (170) |
bpm indicates beats per minute; DWS, diastolic wall strain; IVRT, isovolumic relaxation time; PRSW, preload recruitable stroke work; PV, pulmonary vein; S/D, systolic/diastolic; SLV, single left ventricle; SRV, single right ventricle; SVRI, systemic vascular resistance index; VA coupling, ventricular‐arterial coupling; V0, ventricular volume axis intercept of end‐systolic pressure volume relationship.
P<0.05 versus controls.
P<0.05 SRV versus SLV.