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Simplified schematic representations of the HSP-70, p53 and NF-kB pathways (a) showing the known effects of LPS (b). c Proposed effects of PFT-µ, including a decrease in HSP-70 expression, decreased NF-kB pathway activation and an unknown effect of the HSP-70/PFT-µ complex (adapted from Hofacer et al. [66]).
