Table 4.

Summary comparison of the characteristics of stimulation targets individually and in combination

Target	Frequency, Hz	Approximate time for analgesic effect to stabilise with stimulation, min	Approximate time for analgesia reversal to stabilise (washout) with stimulation arrest, min	Analgesic effect	Character of analgesia	Increases threshold to cold pain	Attenuates dynamic allodynia
PAG	5–10	15	7.5	yes	Warmth; feeling of contentment	yes	yes
CmPf	70–150	7.5	12.5	yes	Pain better tolerated; paraesthesia provides distractive paraesthesia	no	yes
Combined				yes	both	yes	yes