TABLE 2.
Crude and Multivariate Adjusted HRs for Phototherapy and Covariates
| Variable | Crude HR (95% CI) | P | Adjusted HR (95% CI) | P |
|---|---|---|---|---|
| Any phototherapy | ||||
| No | Reference | Reference | — | |
| Yes | 0.95 (0.68 to 1.32) | .75 | 1.06 (0.78 to 1.45) | .69 |
| Year of birth | ||||
| 1995–2000 | Reference | — | ||
| 2001–2006 | 1.05 (0.88 to 1.24) | .60 | 1.09 (0.95 to 1.26) | .23 |
| 2007–2011 | 1.02 (0.77 to 1.36) | .89 | 1.08 (0.72 to 1.63) | .71 |
| Maternal age | ||||
| <20 y | 0.67 (0.46 to 0.95) | .03 | 0.68 (0.49 to 0.95) | .02 |
| 20 to <25 y | 0.83 (0.66 to 1.03) | .09 | 0.84 (0.71 to 1) | .05 |
| 25 to <30 y | 0.87 (0.73 to 1.05) | .16 | 0.89 (0.74 to 1.07) | .22 |
| 30 to <35 y | Reference | Reference | — | |
| 35 to <40 y | 0.85 (0.68 to 1.06) | .15 | 0.83 (0.65 to 1.07) | .15 |
| ≥40 y | 1.01 (0.7 to 1.45) | .96 | 0.97 (0.66 to 1.42) | .88 |
| Race or ethnicity | ||||
| White | Reference | Reference | — | |
| Asian | 0.35 (0.27 to 0.46) | <.0005 | 0.35 (0.29 to 0.42) | <.0005 |
| Black | 0.77 (0.59 to 0.99) | .04 | 0.79 (0.53 to 1.18) | .25 |
| Hispanic | 0.54 (0.45 to 0.66) | <.0005 | 0.56 (0.44 to 0.7) | <.0005 |
| Other | 0.63 (0.45 to 0.88) | .007 | 0.64 (0.47 to 0.87) | .01 |
| Gestational age | ||||
| <38 wk | Reference | — | ||
| ≥38 wk | 1.07 (0.85 to 1.33) | .57 | 1.17 (1.01 to 1.35) | .04 |
| Birth wt | ||||
| <2500 g | 0.92 (0.6 to 1.41) | .72 | 0.89 (0.57 to 1.41) | .63 |
| 2500 to <4200 g | Reference | Reference | — | |
| ≥4200 g | 1.4 (1.09 to 1.78) | .007 | 1.29 (1.04 to 1.61) | .02 |
| Direct antiglobulin test | ||||
| Not done | 0.93 (0.79 to 1.09) | .37 | 0.94 (0.82 to 1.07) | .35 |
| Negative | Reference | — | ||
| Positive | 1.05 (0.63 to 1.74) | .85 | 1.13 (0.69 to 1.86) | .63 |
| Maximum total serum bilirubin, mg/dL | ||||
| Not done or <10 | Reference | — | ||
| 10–14.9 | 0.9 (0.72 to 1.13) | .36 | 0.92 (0.8 to 1.05) | .20 |
| 15–19.9 | 0.72 (0.55 to 0.94) | .02 | 0.74 (0.53 to 1.02) | .07 |
| ≥20 | 1.03 (0.63 to 1.66) | .92 | 1.05 (0.7 to 1.59) | .81 |
—, no point estimates, 95% CI, or P value for the reference categories of each risk factor.