Dose- and time-responsive cell viability (in % of control) of PC12 cell line affected by different treatments: a) glutamate (1–20 mM) alone, b) curcumin (1–50 µM) alone, and c) combined therapy with glutamate 20 mM and curcumin 1–50 µM.
* and # indicate significant difference from the control after incubation for 24 and 48 h, respectively. Singlet, doublet, and triplet symbols indicate statistical difference at confidence level of p<0.05, p<0.01, and p<0.001, respectively (N=6)