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Luriferase assay indicates the ex vivo activity of Tbab1‐4 and Tbab2‐4 as TNFα inhibitors. Tbab1‐4, Tbab2‐4 and DS119 were incubated with TNFα before they were added to ΗΕΚ293Τ cells. TNFα stimulates NFκB and other signaling elements leading to the expression of luciferase. We measured the level of TNFα as the readout of luciferin luminance signals. The data were reported as means ± standard errors from three independent experiments.
