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Effect of N‐terminal mutations on the features of the NColE7 protein
| NColE7 variant | Im7 binding | DNA binding | Cytotoxicity | In vitro DNA cleaving activity | Solution structure |
|---|---|---|---|---|---|
| NColE72, 3, 13, 15, 26 | + | + | + | +++ | |
| W464A‐mutants2, 3 | + | + | + | + | Partially disordered |
| T454A/K458A3 | + | + | + | + | NColE7‐like |
| ΔN4‐NColE725 | + | + | − | − | NColE7‐like |
| ΔN25‐NColE725 | + | + | − | − | Partially disordered |
| ΔN45‐NColE724 | + | − | − | − | Partially disordered |
| ΔN69‐NColE724 | − | − | − | − | Partially disordered |
