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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: JAMA Psychiatry. 2016 Oct 1;73(10):1015–1022. doi: 10.1001/jamapsychiatry.2016.1728

Table 2. Suicide attempt and violent offending in offspring in relation to having at least 1 parent affected by a specific psychiatric diagnosis or a history of suicide attempt a.

Parental psychiatric diagnosis or suicide attempt IRR (95% CI)
Suicide attempt Violent offending
Any mental disorders 2.53 (2.47-2.58) 2.25 (2.21-2.30)
Organic mental disorders 2.20 (2.05-2.35) 1.91 (1.78-2.04)
  Dementia in Alzheimer disease 1.79 (1.45-2.17) 1.18 (0.92-1.48)
  Vascular dementia 1.42 (1.03-1.91) 1.70 (1.27-2.23)
Any substance use disorders 2.93 (2.84-3.01) 2.87 (2.80-2.94)
  Alcohol misuse 2.85 (2.76-2.93) 2.76 (2.68-2.84)
  Cannabis misuse 3.57 (3.25-3.92) 4.05 (3.72-4.39)
Broadly-defined schizophrenia b 2.11 (2.01-2.22) 1.86 (1.78-1.95)
  Narrowly-defined schizophrenia c 2.35 (2.16-2.55) 2.01 (1.85-2.18)
  Schizoaffective disorder 2.10 (1.81-2.41) 1.55 (1.33-1.79)
Mood disorders 2.04 (1.97-2.10) 1.64 (1.59-1.70)
  Bipolar disorder 1.58 (1.45-1.72) 1.35 (1.24-1.46)
  Recurrent depressive disorder 1.88 (1.78-1.99) 1.53 (1.44-1.62)
  Single and recurrent depressive disorders 2.00 (1.93-2.07) 1.62 (1.57-1.68)
Anxiety and somatoform disorders 2.62 (2.56-2.69) 2.34 (2.28-2.40)
  Obsessive-compulsive disorder 1.89 (1.53-2.30) 1.32 (1.04-1.64)
Specific personality disorders 2.62 (2.55-2.70) 2.31 (2.25-2.38)
  Borderline type personality disorder 2.86 (2.59-3.16) 2.36 (2.13-2.61)
  Antisocial personality disorder 3.96 (3.72-4.21) 3.62 (3.41-3.84)
Attempted suicide 3.42 (3.29-3.55) 3.31 (3.19-3.44)

Abbreviation: IRR, incidence rate ratio.

a

Adjusted for offspring sex and age, calendar year, and the interactions between these variables. Reference group: neither parent had the particular exposure of interest.

b

Schizophrenia and related disorders.

c

Schizophrenia only.