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. 2016 Oct 25;11(10):e0165426. doi: 10.1371/journal.pone.0165426

Table 1. The seven most frequent alleles of HLA-A, -B and -DRB1 loci.

Allele Patients (1,464) Controls (10,000) p-value Pc
n Frequency (%) n Frequency (%)
A11 542 18.51 3294 16.47 0.006 0.145
A1 116 3.96 991 4.96 0.019 0.426
A24 480 16.39 3123 15.62 0.277 1.000
A3 138 4.71 1036 5.18 0.302 1.000
A30 235 8.03 1670 8.35 0.591 1.000
A2 881 30.09 5980 29.9 0.846 1.000
A33 196 6.69 1327 6.64 0.905 1.000
B62 150 5.12 1434 7.17 <0.001 0.001
B51 213 7.28 1590 7.95 0.211 1.000
B35 163 5.57 1232 6.16 0.230 1.000
B61 178 6.08 1334 6.67 0.248 1.000
B46 179 6.11 1289 6.45 0.518 1.000
B60 198 6.76 1294 6.47 0.547 1.000
B13 364 12.43 2482 12.41 0.976 1.000
DRB1*15 440 15.03 3846 19.23 <0.001 <0.001
DRB1*4 405 13.83 2167 10.84 <0.001 <0.001
DRB1*11 260 8.88 1291 6.46 <0.001 <0.001
DRB1*9 330 11.27 2571 12.86 0.016 0.270
DRB1*12 317 10.83 1992 9.96 0.148 1.000
DRB1*14 179 6.11 1132 5.66 0.327 1.000
DRB1*7 361 12.33 2481 12.41 0.928 1.000