Table 1. The seven most frequent alleles of HLA-A, -B and -DRB1 loci.
Allele | Patients (1,464) | Controls (10,000) | p-value | Pc | ||
---|---|---|---|---|---|---|
n | Frequency (%) | n | Frequency (%) | |||
A11 | 542 | 18.51 | 3294 | 16.47 | 0.006 | 0.145 |
A1 | 116 | 3.96 | 991 | 4.96 | 0.019 | 0.426 |
A24 | 480 | 16.39 | 3123 | 15.62 | 0.277 | 1.000 |
A3 | 138 | 4.71 | 1036 | 5.18 | 0.302 | 1.000 |
A30 | 235 | 8.03 | 1670 | 8.35 | 0.591 | 1.000 |
A2 | 881 | 30.09 | 5980 | 29.9 | 0.846 | 1.000 |
A33 | 196 | 6.69 | 1327 | 6.64 | 0.905 | 1.000 |
B62 | 150 | 5.12 | 1434 | 7.17 | <0.001 | 0.001 |
B51 | 213 | 7.28 | 1590 | 7.95 | 0.211 | 1.000 |
B35 | 163 | 5.57 | 1232 | 6.16 | 0.230 | 1.000 |
B61 | 178 | 6.08 | 1334 | 6.67 | 0.248 | 1.000 |
B46 | 179 | 6.11 | 1289 | 6.45 | 0.518 | 1.000 |
B60 | 198 | 6.76 | 1294 | 6.47 | 0.547 | 1.000 |
B13 | 364 | 12.43 | 2482 | 12.41 | 0.976 | 1.000 |
DRB1*15 | 440 | 15.03 | 3846 | 19.23 | <0.001 | <0.001 |
DRB1*4 | 405 | 13.83 | 2167 | 10.84 | <0.001 | <0.001 |
DRB1*11 | 260 | 8.88 | 1291 | 6.46 | <0.001 | <0.001 |
DRB1*9 | 330 | 11.27 | 2571 | 12.86 | 0.016 | 0.270 |
DRB1*12 | 317 | 10.83 | 1992 | 9.96 | 0.148 | 1.000 |
DRB1*14 | 179 | 6.11 | 1132 | 5.66 | 0.327 | 1.000 |
DRB1*7 | 361 | 12.33 | 2481 | 12.41 | 0.928 | 1.000 |