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. 2016 Aug 5;65(11):3505–3515. doi: 10.2337/db16-0634

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© 2016 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

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Mice transplanted with α4(S988A) bone marrow display greater revascularization. Irradiated, wild-type C57 mice transplanted with α4(WT) or α4(S988A) bone marrow as indicated were made diabetic and subjected to HLI. Blood perfusion was measured after 3 weeks by LDPI. A: Illustrated are representative scans. NI, nonischemic limb; I, ischemic limb. B: The perfusion in the ischemic limb was normalized to that of the nonischemic limb and a percentage recovery calculated for each mouse. WT, n = 8; S988A, n = 5. *P < 0.05.