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Molecular structures of (A) PGF2α, (B) latanoprost, and (C) LBN.
Notes: Both latanoprost and LBN contain a latanoprost acid backbone. In contradistinction to latanoprost, however, LBN integrates an NO-donating moiety (red) in lieu of an isopropyl ester.
Abbreviations: PGF2α, prostglandin F2α; LBN, latanoprostene bunod; NO, nitric oxide.
