Table 1.

Baseline Demographic and Clinical Characteristics

		Pilot Cohort		Replication Cohort		Total Population
		Stable CAD	ACS	Stable CAD	ACS	Stable CAD	ACS
		n=10	n=14	n=56	n= 20	n=66	n= 34
Demographic Profile
	Median Age (25th, 75th %)	66 (53, 75)	64 (51, 68)	59 (52, 64)	66 (58, 75)	59.5 (53.0, 65.2)	64.5 (56.8, 73.3)
	Male	8 (80 %)	7 (50 %)	39 (69%)	10 (50%)	47 (71.2 %)	17 (50 %)
	Caucasian	8 (80 %)	8 (57 %)	49 (88%)	15 (75%)	57 (86.4 %)	23 (67.6 %)
Cardiac Risk Factors
	DM	2 (20 %)	6 (43 %)	8 (14%)	5 (25%)	10 (15.2 %)	11 (32.4 %)
	HTN	7(70 %)	9 (64 %)	32 (57%)	16 (80%)	39 (59.1 %)	25 (73.1 %)
	Dyslipidemia	8 (80 %)	11 (79 %)	31 (55%)	11 (55%)	39 (59.1 %)	22 (64.7 %)
	Median LDL (25th, 75th %)	85 (70, 114)	100.5 (71, 117)	109.0 (78, 131)	99.0 (71, 119)	105.0 (77.0, 129.5)	100.0 (71.0, 118.0)
	Tobacco smoking- active	2 (20 %)	3 (21 %)	5 (4%)	9 (45%)	7 (10.6 %)	12 (35.3 %)
	Tobacco smoking- previous	5 (50 %)	5 (35 %)	17 (30%)	5 (25%)	22 (33.3 %)	10 (29.4 %)
	FHx- Premature CAD	2 (20%)	2 (14 %)	12 (21%)	4 (20%)	14 (21.2%)	6 (17.6%)
Cardiovascular Disease
	Prior CABG	4 (40 %)	2 (14 %)	2 (4%)	2 (10 %)	6 (9.1 %)	4 (11.8 %)
	Prior PCI	4 (40 %)	8 (57 %)	2 (4 %)	2 (10 %)	6 (9.1 %)	10 (29.4 %)
	Prior LV dysfunction	2 (20 %)	3 (21 %)	3 (5 %)	1 (5 %)	5 (7.6 %)	4 (11.8 %)
	Symptomatic PAD	2 (20%)	1 (7%)	0	3 (15 %)	2 (3.0 %)	4 (11.8 %)
	Prior CVA/TIA	1 (10 %)	2 (14 %)	3 (5 %)	2 (10 %)	4 (6.1 %)	4 (11.8 %)
	ESRD	0	1 (7 %)	1 (2 %)	0	1 (1.5 %)	1 (1.5 %)
Presentation Details
	Positive Cardiac Biomarkers	1/10 (10 %)	11/14 (79 %)	0 (0%)	20 (100%)	1 (1.5 %)	31 (91.2 %)
	Revascularization	1/10 (10 %)	9/14 (64 %)	0 (0%)	20 (100%)	1 (1.5 %)	29 (85.3 %)