Table 2.

Adjusted Hazard Ratios for Incident Stroke Per 1 Standard Deviation Increase in Hepatocyte Growth Factor, Multi-Ethnic Study of Atherosclerosis, 2000–2013

Stroke Model*	Number of Strokes/Total Population	Hazard Ratio (95% Confidence Interval)	P Value
All stroke
Model 1	233/6711	1.30 (1.15–1.47)	<0.0001
Model 2	229/6604	1.17 (1.03–1.34)	0.02
Ischemic stroke
Model 1	183/6711	1.34 (1.17–1.53)	<0.0001
Model 2	179/6604	1.21 (1.04–1.40)	0.01
All ischemic strokes except cardioembolic
Model 1	158/6711	1.33 (1.15–1.54)	0.0001
Model 2	156/6604	1.20 (1.02–1.40)	0.03
Hemorrhagic stroke
Model 1	39/6711	1.23 (0.90–1.68)	0.2
Model 2	39/6604	1.09 (0.78–1.53)	0.6
Other stroke
Model 1	11/6711	0.99 (0.53–1.85)	1.0
Model 2	11/6604	0.85 (0.43–1.65)	0.6

^*Cox regression with outcome incident stroke and predictor 1 standard deviation (259 pg/ml) increase of hepatocyte growth factor.

Model 1 - Adjusted for age (continuous), race/ethnicity (Non-Hispanic white American, Chinese American, African American, Hispanic American), and sex (male, female).

Model 2 - Adjusted for Model 1 plus baseline values of body mass index (continuous), smoking status (current, former, never), diabetes mellitus (yes, no), systolic blood pressure (continuous), antihypertensive medication use (yes, no), high-density lipoprotein cholesterol (continuous), total cholesterol (continuous), low-density lipoprotein cholesterol (continuous), triglycerides (continuous), lipid medication use (yes, no), and study cite (Baltimore; Chicago; Forsyth County, North Carolina; Los Angeles; New York, New York; and St Paul, Minnesota).