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The major PAMPs that are currently being used or being investigated as potential adjuvants.
| PAMP | Microorganism of origin | Host receptor | Adaptive immune branch activated |
|---|---|---|---|
| LPS | Gram negative bacteria | TLR4/inflammasome | Humoral/cellular |
| Flagellin | Flagellated bacteria | TLR5/inflammasome | Humoral/cellular |
| ssRNA agonists | ssRNA viruses | TLR7/TRL8 | Humoral/cellular |
| CpG | microorganisms | TLR9 | Humoral/cellular |
