Table 5.
Initial TK selectivity profile of the cembranoid carbamate 20.
| Kinase | Mean % inhibition at 10 μM |
|---|---|
| ABL1 | 31 |
| ALK | 10 |
| AXL | 11 |
| EGFR (ErbB1) | 9 |
| ERBB2 (HER2) | 22 |
| FGGR1 | 49 |
| IGF1R | 30 |
| MET | 84 |
| MST1R (RON) | 31 |
| ROS1 | 3 |
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