Table 2.
Initial data | 6th month | End of treatmenta | p value 6th month vs. initial data | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
incrPD | stPD | p | incrPD | stPD | p | incrPD | stPD | p | incrPD | stPD | |
Number of patients | 29 | 75 | 25 | 66 | 25 | 65 | |||||
twKt/V | 2.08 ± 0.38 | 2.40 ± 0.58 | 0.008 | 2.13 ± 0.45 | 2.20 ± 0.43 | 0.527 | 1.77 ± 0.50 | 2.01 ± 0.35 | 0.007 | 0.672 | 0.012 |
twCrCl (l/w/1.73 m2) | 81 ± 15 | 85 ± 18 | 0.341 | 83 ± 19 | 77 ± 20 | 0.192 | 66 ± 27 | 62 ± 21 | 0.460 | 0.485 | 0.004 |
Residual renal creatinine clearance | 7.55 ± 1.94 | 7.36 ± 2.21 | 0.690 | 7.74 ± 2.97 | 5.81 ± 2.72 | 0.004 | 5.39 ± 3.85 | 2.62 ± 3.35 | 0.001 | 0.797 | <0.001 |
Peritoneal creatinine clearance | 1.98 ± 0.70 | 2.80 ± 0.93 | <0.001 | 2.02 ± 0.63 | 3.22 ± 1.21 | <0.001 | 2.16 ± 0.68 | 4.08 ± 1.37 | <0.001 | 0.297 | <0.001 |
Renal + peritoneal creatinine clearance | 9.53 ± 1.99 | 10.16 ± 2.52 | 0.231 | 9.77 ± 2.87 | 9.04 ± 2.63 | 0.255 | 7.55 ± 3.66 | 6.71 ± 2.82 | 0.246 | 0.600 | 0.015 |
Peritoneal contribution to total creatinine clearance (%) | 21 ± 7 | 28 ± 8 | <0.001 | 22 ± 10 | 38 ± 19 | <0.001 | 32 ± 13 | 70 ± 30 | <0.001 | 0.448 | <0.001 |
Residual urea renal clearance | 4.55 ± 1.23 | 3.81 ± 1.35 | 0.014 | 4.63 ± 1.42 | 3.12 ± 1.67 | <0.001 | 3.27 ± 2.09 | 1.4 ± 1.85 | <0.001 | 0.778 | <0.001 |
Peritoneal urea clearance | 2.44 ± 0.78 | 4.50 ± 1.38 | <0.001 | 2.54 ± 0.79 | 4.68 ± 1.18 | <0.001 | 2.66 ± 0.81 | 5.66 ± 1.52 | <0.001 | 0.393 | 0.155 |
Renal + peritoneal urea clearance | 6.99 ± 1.15 | 8.30 ± 1.93 | <0.001 | 7.17 ± 1.32 | 7.80 ± 1.54 | 0.073 | 5.94 ± 1.80 | 7.06 ± 1.42 | 0.246 | 0.490 | 0.018 |
Peritoneal contribution to total urea clearance (%) | 35 ± 11 | 54 ± 11 | <0.001 | 36 ± 11 | 61 ± 16 | <0.001 | 47 ± 16 | 82 ± 21 | <0.001 | 0.757 | <0.001 |
Creatinine renal clearance/urea renal clearance | 1.70 ± 0.43 | 2.08 ± 0.92 | 0.007 | 1.69 ± 0.55 | 2.16 ± 1.24 | 0.007 | 1.65 ± 0.33 | 2.17 ± 1.58 | 0.051 | 0.678 | 0.080 |
Residual renal function | 6.08 ± 1.47 | 5.61 ± 1.49 | 0.160 | 6.20 ± 2.02 | 4.48 ± 2.12 | <0.001 | 4.36 ± 2.96 | 2.03 ± 2.55 | < 0.001 | 0.792 | <0.001 |
All values except Kt/V are normalized to 1.73 m2 of body surface area
Statistically significant values are in bold
Statistically non-significant values are in italic
twKt/V total weekly Kt/V, twCrCl total weekly creatinine clearance
aLast value before changing from incrPD to stPD or stopping PD