TABLE 3 .

Summary of strong positive correlations identified between the relative abundances of species and the levels of metabolites in kefir

Species	Compound(s)	R value	P value
			Unadjusted	FDR adjusteda
Leuconostoc mesenteroides	2,3-Butanedione	0.79	0.0005	0.011
Lactobacillus kefiranofaciens	2-Nonanone	0.79	0.0005	0.011
Lactobacillus helveticus	Acetic acid	0.75	0.0013	0.017
Leuconostoc mesenteroides	2-Methyl-1-butanol	0.74	0.0015	0.017
Lactobacillus kefiranofaciens	Hexanoic acid	0.71	0.0033	0.024
Lactobacillus kefiranofaciens	2-heptanone	0.71	0.0033	0.024
Lactobacillus kefiranofaciens	Octanoic acid	0.70	0.0040	0.024
Lactobacillus kefiranofaciens	Acids	0.68	0.0049	0.024
Lactobacillus kefiranofaciens	n-Decanoic acid	0.68	0.0049	0.024
Saccharomyces cerevisiae	Nonanal	0.66	0.0080	0.035
Lactobacillus kefiranofaciens	Ethyl decanoate	0.65	0.0089	0.035
Lactobacillus kefiranofaciens	Esters	0.64	0.0099	0.035
Saccharomyces cerevisiae	Ethyl acetate	0.63	0.0110	0.035
Saccharomyces cerevisiae	3-Methyl-butanol	0.63	0.0118	0.035
Acetobacter pasteurianus	2-Methyl-1-butanol	0.63	0.0126	0.035
Saccharomyces cerevisiae	Phenylethyl alcohol	0.62	0.0134	0.035
Saccharomyces cerevisiae	Octanal	0.62	0.0141	0.035
Acetobacter pasteurianus	Nonanoic acid	0.60	0.0169	0.040
Lactobacillus kefiranofaciens	Phenylethyl alcohol	0.60	0.0179	0.040
Saccharomyces cerevisiae	Alcohols	0.59	0.0203	0.040
Acetobacter pasteurianus	Acetic acid	0.59	0.0206	0.040
Lactobacillus helveticus	2,3-Butanedione	0.57	0.0255	0.040
Acetobacter pasteurianus	Ethyl butanoate	0.57	0.0268	0.040
Lactobacillus kefiranofaciens	Ethyl hexanoate	0.57	0.0279	0.040
Lactobacillus helveticus	3-Methyl-butanol	0.56	0.0283	0.040
Saccharomyces cerevisiae	Ethyl decanoate	0.56	0.0283	0.040
Lactobacillus kefiranofaciens	Ethyl butanoate	0.56	0.0292	0.040
Acetobacter pasteurianus	Ethyl hexanoate	0.56	0.0314	0.040
Lactobacillus kefiranofaciens	Nonanoic acid	0.56	0.0315	0.040
Lactobacillus kefiranofaciens	2-Undecanone	0.56	0.0315	0.040
Lactobacillus kefiranofaciens	Ethyl octanoate	0.55	0.0321	0.040
Lactobacillus kefiranofaciens	3-Methyl-butanol	0.55	0.0321	0.040
Acetobacter pasteurianus	Acids	0.55	0.0324	0.040
Acetobacter pasteurianus	Hexanoic acid	0.54	0.0368	0.044
Acetobacter pasteurianus	2,3-Butanedione	0.54	0.0375	0.044
Acetobacter pasteurianus	Ethyl acetate	0.54	0.0381	0.044
Saccharomyces cerevisiae	Esters	0.53	0.0413	0.046
Leuconostoc mesenteroides	Acetic acid	0.53	0.0419	0.046
Lactobacillus helveticus	2-Methyl-1-butanol	0.53	0.0433	0.046
Saccharomyces cerevisiae	2-Undecanone	0.53	0.0435	0.046
Lactobacillus kefiranofaciens	Ethyl acetate	0.52	0.0478	0.048
Acetobacter pasteurianus	Octanoic acid	0.52	0.0478	0.048

^aFDR, false discovery rate.