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Comparison of sinotrial pacemaker cells and chamber myocytes. (A) Morphological comparison of a SAN myocyte (phase contrast) and a ventricular myocyte, which was immunochemically stained for Ryr2 expression. Bar represents 25 μm. (B) Comparison of the action potentials of a SAN myocyte (left) and a ventricular myocyte (right). (C) Transcriptional network, which determines SAN development. Panel C was adapted from [15].
