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. 2016 Jun 9;116(2):272–284. doi: 10.1160/TH15-11-0891

Table 3:

Most abundant ion channel-related transcripts in megakaryoblastic and megakaryocytic cell lines. Data represent expression of mRNA transcripts relative to endogenous control. Results are expressed as mean values (see Suppl. Table 1 for SEM, available online at www.thrombosis-online.com). nd, not detected; td, trace detection.

Gene symbol Full name Relative expression
CHRF HEL MEG-01
CLIC1 Chloride intracellular channel 1 0.2338 0.0662 0.0827
CLNS1A Chloride conductance, nucleotide sensitive protein 1A 0.1066 0.0683 0.0750
CLIC4 Chloride intracellular channel 4 0.0606 0.0962 0.0503
VDAC2 Voltage-dependent anion channel 2 0.0944 0.0611 0.0315
VDAC3 Voltage-dependent anion channel 3 0.0465 0.0412 0.0859
FXYD5 FXYD domain-containing ion transport regulator 5; dysadherin 0.0425 0.0675 0.0294
TOMM40 Mitochondrial import receptor subunit homolog; Protein haymaker, p38.5 0.0305 0.0300 0.0568
CLIC2 Chloride intracellular channel 2 0.0005 0.0155 0.0499
CLCA1 CLCA family member 1, chloride channel regulator nd nd 0.0449
GRINA Protein lifeguard 1; Glutamate [NMDA] receptor-associated protein 1 0.0078 0.0276 0.0254
PKD1 Polycystin-1; TRPP1 0.0262 0.0067 0.0073
VDAC1 Voltage-dependent anion channel 1; porin 0.0021 0.0022 0.0245
KCTD15 Potassium channel tetramerization domain-containing protein 15 0.0007 0.0210 0.0116
KCNK17 Potassium channel, subfamily K, member 17; K2p17.1 0.0181 0.0041 td
GJA4 Gap junction protein, alpha 4, 37kDa 0.0123 0.0013 td
GJA5 Gap junction protein, alpha 5, 40kDa 0.0004 0.0015 td
TMEM38B TRIC type sub-channel B 0.0112 0.0087 0.0118
PIEZO1 Piezo-type mechanosensitive ion channel component; Fam38A 0.0051 0.0110 0.0088
KCNE3 Potassium voltage-gated channel, Isk-related family, member 3; MiRP2 0.0057 0.0105 0.0008
KCNN4 Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; KCa3.1 0.0011 0.0047 0.0104