Figure 2.

Transcriptional Analysis of Endophilin TKO and 1,2 DKO Hippocampi

(A–D) Heatmap showing the expression of ataxia- (A: TKO; C: 1,2 DKO) and Parkinson’s-disease-related genes (B: TKO; D: 1,2 DKO).

(E) Pathway analysis of the transcriptional signatures of TKO hippocampi using the IPA software. The ten most significantly enriched pathways based on Fisher exact test p values (x axis) are presented.

(F) The RNA sequencing results verified by qRT-PCR for named genes in TKO samples.

See also Figure S2 and Tables S1, S2, S3, S4, S5, S6, S7, and S8.