Table 2.
The mean change in brain activity from regions-of-interest within the left and right frontal cortices for the Word Memory and Design Memory modules of the neurocognitive test. Regions were obtained from cluster analysis (k-means clustering) of the oxy-hemoglobin reconstructions with a threshold of p<0.05 and minimum cluster size of 10 voxels. The deoxy-hemoglobin values within this same region are also provided. For each region, the anatomical label and Brodmann area [if applicable] is provided based on the MNI coordinate of the center of the region. Abbreviations used IFG [inferior frontal gyrus], MFG [middle frontal gyrus], MTG [middle temporal gyrus], STG [superior temporal gyrus]
| Concussed (N=9)
|
Control (N=5)
|
Difference (Concussed-Controls)
|
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Region | [X | Y | Z] | Cluster size (mm^2) |
Oxy- hemoglobin |
Deoxy- hemoglobin |
[X | Y | Z] | Cluster size (mm^2) |
Oxy- hemoglobin |
Deoxy- hemoglobin |
[X | Y | Z] | Cluster size (mm^2) |
Oxy- hemoglobin |
Deoxy- hemoglobin |
|||
| Word memory presentation | |||||||||||||||||||||
| Right | IFG[BA 47] | 48 | 20 | −4 | 53 | −6.2 | 0.9 | MTG[BA 22] | 60 | 8 | −4 | 38 | −4.5 | - | IFG[BA 47] | 56 | 16 | −2 | 36 | −06 | 0.0 |
| Left | IFG[BA 47] | −21 | 30 | −8 | 18 | −1.2 | MFG | −22 | 35 | −13 | 17 | −2.1 | 1.1 | - | - | - | - | - | - | - | |
| Word memory recall | |||||||||||||||||||||
| Right | - | - | - | - | - | - | MFG | 29 | 57 | 7 | 41 | 3.9 | −1.2 | - | - | - | - | - | - | ||
| Left | MFG | −6 | 55 | −4 | 90 | 6.9 | −1.8 | IFG | −51 | 30 | −10 | 61 | 12.3 | −2.9 | IFG | −46 | 32 | −10 | 61 | −1.7 | 0.1 |
| Word memory delayed recall | |||||||||||||||||||||
| Right | MFG | 30 | 51 | 3 | 50 | 5.0 | −1.4 | - | - | - | - | - | - | - | - | - | - | - | - | ||
| Left | IFG | −53 | 22 | −6 | 74 | 10.6 | −1.4 | MFG [BA 10] | −3 | 60 | −3 | 85 | 7.9 | −3.1 | MFG | −41 | 51 | −6 | 42 | 1.7 | −0.1 |
| Design memory presentation | |||||||||||||||||||||
| Right | STG | 61 | 7 | −8 | 29 | 2.9 | −2.2 | IFG [BA 47] | 56 | 23 | −10 | 29 | 2.4 | −1.4 | MTG [BA 21] | 60 | 3 | −16 | 35 | −0.2 | 0.0 |
| Left | IFG | −46 | 43 | 0 | 34 | − | −1.6 | IFG | −49 | 26 | −8 | 9 | 1.9 | −1.5 | - | - | - | - | - | - | |
| Design memory recall | |||||||||||||||||||||
| Right | MFG | 37 | 43 | −3 | 55 | - | −1.5 | MFG | 28 | 50 | 8 | 43 | 2.4 | −1.3 | MFG | 32 | 43 | −5 | 51 | −0.5 | 0.0 |
| Left | IFG | −40 | 27 | −15 | 13 | 2.1 | − | MFG | −9 | 55 | −4 | 24 | 2.3 | - | - | - | - | - | - | - | |
| Design memory delayed recall | |||||||||||||||||||||
| Right | IFG | 54 | 22 | −13 | 36 | 4.7 | −2.0 | IFG [BA 47] | 53 | 35 | −13 | 26 | 2.0 | −1.7 | STG | 44 | 3 | −12 | 53 | 1.2 | 0.0 |
| Left | MFG [BA 11] | −44 | 35 | −13 | 16 | 2.8 | −1.6 | IFG [BA 47] | −50 | 24 | −2 | 6 | 2.1 | −1.6 | - | - | - | - | - | - | |