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. Author manuscript; available in PMC: 2016 Oct 26.
Published in final edited form as: Obesity (Silver Spring). 2016 Jul 26;24(9):1946–1954. doi: 10.1002/oby.21592

Figure 7.

Figure 7

HRP treatment may increase adiponectin and insulin signaling in obese mice. (A) Adiponectin mRNA levels in adipose tissue. Correlation between plasma adipoH levels and body weight in mice on (B) N and (C) HF/HC diet. (D) Total Akt and (E) p-Akt protein levels in adipose tissue. Equal loading of 10 µL of plasma or 20 µg of proteins was done in each well. Data are normalized to s16 mRNA levels and are presented as mean ± SE with n = 9–13 per group for adiponectin mRNA. n = 8 per group for the correlation analysis between plasma adipoH and body weight. Data are normalized to tubulin protein levels and are presented as mean ± SE with n = 4–7 per group for Akt and p-Akt. *P < 0.05 compared with N diet; †P < 0.05 compared with saline. HF/HC, high-fat/high-carbohydrate diet; HRP, handle region peptide; adipoH, high molecular weight (HMW) adiponectin; N, normal; PGF, perigonadal fat; PRF, perirenal fat; SCF, abdominal subcutaneous fat.