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. 2016 Oct 26;6:35634. doi: 10.1038/srep35634

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) K_i^*/K_s versus i. i denotes the universal ranking of each amino acid change and range from the most exchangeable pairs (i = 1) to the least exchangeable pairs (i = 75)⁶⁷. K₇₅^*/K_s is equivalent to K_a/K_s. K₁₀^*/K_s is almost twice the value of K_a/K_s. (b) Scatter plot of K_h/K_s versus K_a/K_s for 53 supergenes between A. aureum and A. speciosum. Each supergene contains 100 orthologs with similar K_a values.