Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Metabolization and excretion
| Process | Parameter | |
|---|---|---|
| CYP1A2 metabolization | 17 ml/min (intrinsic clearance) | |
| Biliary secretion | 1.03 ml/min/kg | |
| Renal excretion |
GFR specific: 0.266 ml/min/g of organ TBS: 0.57 l/min |
|
These parameters have been estimated from the plasma drug concentration. GFR, glomerular filtration rate; TBS, tubular secretion
