Table 2.
Correlations between the expression levels of 3 candidate genes in 24 ovarian cancer cell lines and the IC50 of 8 anti-cancer agents
| CCNA1 | TGM2 | PEA15 | |
|---|---|---|---|
| Paclitaxel | 0.43 (P = 0.038*) § | 0.33 (P = 0.10) § | 0.19 (P = 0.37) § |
| Doxorubicin | 0.45 (P = 0.027*) | 0.02 (P = 0.93) | 0.05 (P = 0.80) |
| 5-Fluorouracil | 0.53 (P = 0.008*) | 0.21 (P = 0.32) | −0.06 (P = 0.78) |
| Carboplatin | 0.09 (P = 0.69) | 0.20 (P = 0.33) | 0.14 (P = 0.49) |
| Cisplatin | −0.03 (P = 0.88) | 0.09 (P = 0.68) | 0.03 (P = 0.87) |
| Etoposide | 0.29 (P = 0.18) | 0.20 (P = 0.35) | 0.04 (P = 0.85) |
| Topotecan | 0.20 (P = 0.36) | −0.03 (P = 0.88) | −0.06 (P = 0.80) |
| Camptothecin | 0.19 (P = 0.37) | 0.04 (P = 0.84) | 0.006 (P = 0.98) |
§
Pearson correlation coefficient and P value of two-tailed t-test.
*
Correlation is significant at P ≤ 0.05.