Table 1.
Schedule of measurements and activities by visit for the ISAR study
| Baseline examination | Follow-up (FU) visits | ||
|---|---|---|---|
| T O (inclusion in the study) | T 24 months | T 6y | |
| Interviewer/Questionaires | |||
| Informed consent | X | ||
| contact information | X | X | X |
| sociodemographic | X | X | X |
| Education and employment | X | X | X |
| Vascular access | X | X | X |
| Residual kidney function | X | X | X |
| Dialysis prescription | X | X | X |
| medical history | X | X | X |
| cardiovascular risk factors | X | X | X |
| Family history of CVD | X | X | X |
| history of prior transplantations | X | X | X |
| Physical activity | X | X | X |
| MOCA | X | X | X |
| CDR | X | X | X |
| Restless legs score | X | X | X |
| Oral medications | X | X | X |
| Examination | |||
| Height, weight, BMI, upper arm circumference | X | X | X |
| Blood pressure | X | X | X |
| Procedures | |||
| 12-lead holter ECG (24h) | X | ||
| 24-h holter blood pressure | X | ||
| Pulse wave velocity (single measurement) | X | X | |
| Pulse wave analysis (single measurement) | X | X | |
| Pulse wave velocity (24h) | X | ||
| Pulse wave analysis (24h) | X | ||
| Retinal vessel analysis (static examination) | X | ||
| Retinal vessel analysis (dynamic examination) | X | ||
| Blood tests (prior to dialysis, fasting), midweek dialysis session | |||
| Serum blood sampling (frozen at −80 °C) | X | X | X |
| EDTA blood sampling (frozen at −80°) | X | X | X |
| Clinical follow up | |||
| Hospitalizations (cardiovascular, infectious…) | X | X | |
| cardiovascular events | X | X | |
| cardiovascular mortality | X | X | |
| total mortality | X | X | |
| dialysis routine blood work (quarterly) | |||
| Glucose, albumin | X | X | X |
| complete blood count | X | X | X |
| Electrolytes (Na, K, Mg, Ca, Phos) | X | X | X |
| Blood gas analysis | X | X | X |
| intact PTH | X | X | X |
| Iron status | X | X | X |
| Kt/V | X | X | X |
| Dialysis treatments | |||
| Dry weight | X | X | X |
| dialysis prescription (duration, frequency, dialyzer) | X | X | X |
| Pre- and Post weights | X | X | X |
| Dialysis flow rates | X | X | X |
| Blood flow rates | X | X | X |
| intravenous medications within dialysis session | X | X | X |