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. 2016 Mar 24;48(4):1399–1407. doi: 10.4143/crt.2015.481

Table 4.

Multivariate analysis of factors affecting PFS and OS in high-risk patients

Risk factor	PFS			OS
Risk factor	HR	95% CI	p-value	HR	95% CI	p-value
Age ≥ 12 mo	0.56	0.12-2.62	0.458	0.27	0.07-1.11	0.069
Unfavorable pathology	1.35	0.47-3.89	0.582	2.98	0.75-11.88	0.122
MYCN amplification	0.97	0.37-2.55	0.949	1.84	0.75-4.50	0.181
PB TH-positive at diagnosis	9.02	2.06-39.50	0.004	3.54	1.26-9.93	0.016

PFS, progression-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; PB, peripheral blood; TH, tyrosine hydroxylase.