Table 3. Clinical randomized controlled trials of long-term oxytocin administration registered with the University Hospital Medical Information Network Clinical Trial Registry, Clinicaltrials.gov, and the Australian New Zealand Clinical Trials Registry.

Starting Date	Registered Database		Institute	Country	Duration	Dosage		Gender	Age	N
						Amount	Frequency
2006.06.	NCT00490802	[53]	Mount Sinai School of Medicine	USA	6 weeks	24 IU	Twice per day	Both	18-60 y.o.	19
2009.06.	ACTRN12609000513213	[55]	University of Sydney	Australia	8 weeks	18 or 24 IU	Twice per day	Male	12-18 y.o.	50
2009.09.	ACTRN12609000784213	[54]	The University of New South Wales	Australia	4 days	12 or 24 IU	Once per day	Male	8-16 y.o.	60
2009.10.	NCT01337687		Albert Einstein College of Medicine	USA	8 weeks	24 IU	Twice per day	Both	18-55 y.o.
2010.12.	ACTRN12611000061932	[57]	University of Sydney	Australia	5 weeks	Upward titration	Twice per day	Both	3-8 y.o.	40
2011.03.	NCT01308749		University of North Carolina	USA	8 weeks	24 or 32 IU	Twice per day	Both	3-17 y.o.	25
2011.03.	UMIN000005211		University of Fukui	Japan	12 weeks	8 or 16 IU	Twice per day	Both	15- y.o.	60
2011.09.	NCT01417026		Children's Hospital of Philadelphia	USA	5 days	24 IU	Once per day	Male	12-17 y.o.	68
2012.03.	UMIN000007122	[56]	The University of Tokyo	Japan	6 weeks	24 IU	Twice per day	Male	18-55 y.o.	20
2012.03.	UMIN000007250		Kanazawa University	Japan	8 weeks	8 IU	Twice per day	Male	15-39 y.o.	30
2012.06.	NCT01624194		Stanford University	USA	4 weeks	24 IU	Twice per day	Both	6-12 y.o.	50
2012.11.	UMIN000009075		Osaka University	Japan	4 weeks	24 IU	Twice per day	Male	6-9 y.o.	40
2013.09.	NCT01908205		Holland Bloorview Kids Rehabilitation Hospital/ University of Minnesota	Canada/ USA	24 weeks	0.4 IU/kg (max 24IU)	Twice per day	Both	10-17 y.o.	60
2013.11.	NCT02007447		University of Sao Paulo General Hospital	Brazil	8 weeks	24 IU	Twice per day	Male	12-18 y.o.	30
2014.03.	NCT02090829		University of Minnesota Department of Psychiatry	USA	5 days	24 IU	Once per day	Male	12-17 y.o.	52
2014.04.	NCT01914939		Massachusetts General Hospital	USA	12 weeks	24 IU	Once per day	Male	18-30 y.o.	150
2014.06.	NCT01788072		Holland Bloorview Kids Rehabilitation Hospital/ McMaster University	Canada	12 weeks	24 IU	Twice per day	Both	18-45 y.o.	146
2014.08.	NCT01944046		University of North Carolina	USA	18 months	Upward titration	Twice per day	Both	3-17 y.o.	300
2014.10.	UMIN000015264		The University of Tokyo/ Kanazawa University/ University of Fukui/ Nagoya	Japan	6 weeks	24 IU	Twice per day	Male	18-55 y.o.	114
2015.06.	UMIN000017876		Osaka University	Japan	4 weeks	24 IU	Twice per day	Male	6-10 y.o.	10

Duration, duration of clinical trial; amount, dosage amount per single administration; frequency, dosage frequency per day; N, number of participants. y.o.: years old.