Table 3.
Adverse events by grade.
| ADVERSE EVENT | 1 | 2 | 3 | 4 |
|---|---|---|---|---|
| ALOPECIA | 1 | 0 | 0 | 0 |
| ANEMIA | 5 | 5 | 4 | 1 |
| ANOREXIA | 6 | 1 | 0 | 0 |
| CONSTIPATION | 0 | 1 | 0 | 0 |
| DEHYDRATION | 3 | 4 | 0 | 0 |
| DIARRHEA | 3 | 1 | 0 | 0 |
| DIZZINESS | 0 | 1 | 0 | 0 |
| EDEMA | 7 | 0 | 0 | 0 |
| EPISTAXIS | 1 | 0 | 0 | 0 |
| FATIGUE | 3 | 4 | 0 | 0 |
| GASTRITIS | 0 | 1 | 0 | 0 |
| HEARING DEFICIT | 0 | 1 | 0 | 0 |
| HYPERURICEMIA | 1 | 0 | 0 | 0 |
| HYPOCALCEMIA | 3 | 0 | 0 | 0 |
| HYPOKALEMIA | 4 | 0 | 0 | 0 |
| HYPOMAGNESEMIA | 8 | 5 | 1 | 0 |
| HYPONATREMIA | 3 | 0 | 0 | 0 |
| HYPOPHOSPHATEMIA | 1 | 2 | 1 | 0 |
| INFECTION | 1 | 0 | 0 | 0 |
| LYMPHOPENIA | 1 | 0 | 0 | 0 |
| MUSCLE WEAKNESS | 3 | 1 | 0 | 0 |
| NAUSEA | 7 | 24 | 0 | 0 |
| NEUTROPENIA | 6 | 4 | 3 | 0 |
| OCULAR/VISUAL CHANGES | 2 | 0 | 0 | 0 |
| PAIN | 2 | 1 | 0 | 0 |
| PROTEINURIA | 1 | 0 | 0 | 0 |
| RASH | 1 | 1 | 0 | 0 |
| TASTE ALTERATION | 1 | 0 | 0 | 0 |
| THROMBOCYTOPENIA | 2 | 1 | 0 | 0 |
| VOMITING | 2 | 8 | 2 | 0 |
| WEIGHT LOSS | 1 | 0 | 0 | 0 |