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The ratio of Bax/Bcl-2 mRNA in HTB140 human melanoma cells 48 h after irradiation with 12C ions of 197 (A) and 382 keV/μm (B). Irradiation doses were 2 - 16 Gy. RPL19 was used as internal control. Mean±SD values, obtained from three experiments, of Bax/Bcl-2 ratios for irradiated samples were normalized to Bax/Bcl-2 ratio for control sample which was set as 1. P*<0.05, **<0.01, ***<0.001 compared to the control.
