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. 2016 Oct;57(13):5525–5534. doi: 10.1167/iovs.16-19691

Figure 6.

Figure 6

Knockdown or inhibition of Thy-1 inhibits VEGF-induced activation of VEGFR2, integrin β3, and Src. Western blots of (A, B) phosphorylated VEGFR2 (top panel, representative images; bottom panel, quantification of densitometry), (C, D) phosphorylated integrin β3 (top panel, representative images; bottom panel, quantification of densitometry), and (E, F) p-Src (top panel, representative images; bottom panel, quantification of densitometry) in CECs transfected with Thy-1 siRNA (A, C, E: *P < 0.05, **P < 0.01, ***P < 0.001 vs. PBS of control siRNA; †P < 0.05, ††P < 0.01 vs. VEGF of control siRNA) or pretreated with Thy-1 blocking peptide (Thy-1 Inh) (B, D, F: ‡P < 0.05 vs. PBS of control; #P < 0.05, ##P < 0.01 vs. VEGF of control) with 30 minutes incubation with VEGF (20 ng/mL) (n = 3–6).