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Thy-1 regulates extracellular matrix protein 7-KC–induced Rac1 activation. (A) Rac1 activity assay in CECs treated with 7-KC at different doses for 30 minutes (top panel, representative images; bottom panel, quantification of densitometry; *P < 0.05 vs. 7-KC at 0 μM) and (B) Rac1 activity assay and phosphorylation of Src in CECs transfected with Thy-1 siRNA or control siRNA and treated with 7-KC (10 μM) or vehicle for 30 minutes (n = 3–6).
