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. Author manuscript; available in PMC: 2016 Oct 26.
Published in final edited form as: Anal Chem. 2016 Feb 5;88(4):2392–2398. doi: 10.1021/acs.analchem.5b04409

Figure 2.

Figure 2

(A) Mass spectrometry image analyzed at a spatial resolution of 200 μm of the primary RIF fragment at m/z 397 and (B) H&E serial section stains of two 12 μm thick sections with 500 μm of the tissue discarded between them of a liver dosed in vitro with RIF. The image of the RIF fragment depicts the homogeneity of the dosing. (C) Average MS/MS spectrum from the dosed tissues with the primary fragment ion m/z 397 circled in red.