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. 2016 Mar 22;25(11):2194–2207. doi: 10.1093/hmg/ddw086

Figure 1.

Figure 1.

Exercise does not induce proper myofibrillar gene expression in C3KO muscles. RT-PCR validation of gene expression levels for sarcomere-associated proteins (Myl2—regulatory myosin light chain 2, cardiac, slow; Ckmt2—mitochondrial creatine kinase; Myom3—myomesin 3; Myo18b—myosin 18b) in plantaris muscles. In each graph, the expression level of the exercised (run) group is graphed relative to the sedentary (sed) controls; the average expression of each gene in the sedentary control group was set at 100% for each genotype. Asterisks indicate statistical significance by two-tailed Student’s t-test with P < 0.05 considered statistically significant. All groups had n = 4.