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. Author manuscript; available in PMC: 2016 Oct 26.
Published in final edited form as: Nat Protoc. 2014 Jan 23;9(2):439–456. doi: 10.1038/nprot.2014.025

Figure 2. Models and data.

Figure 2

The full mRNA self-regulation model is shown in (a). mRNA (m) produces protein P1, which can be transformed into protein P2. P1 is required to produce mRNA, whereas P2 degrades mRNA. P1 and P2 can also be degraded. The reactions that occur according to this model are shown in (b). Fitting of the model to the data (c), which comprise mRNA measurements over time. The second model (d) is based on the first model, but it does not contain protein P2. The relevant reactions are shown in (e).