Effects of 18B12 treatment on CD19 and CD11β. (a, d, g) Spinal cord sections from sham-operated mice did not stain for CD19 or CD11β. (b, e, g) Sections obtained from vehicle-treated animals after spinal cord injury (SCI) demonstrate positive staining for CD19 and for CD11β, mainly localized in inflammatory cells. (c, f, g) 18B12 treatment reduced the degree of positive staining both for B lymphocytes and for CD11β. The figure is representative of at least 3 experiments carried out on different experimental days. Data are expressed as percentage of total tissue area. Data are mean ± SEM of 10 mice from each group.**p < 0.01 vs sham; #
p < 0.1 vs SCI