Skip to main content
. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Reprod Toxicol. 2016 May 18;65:425–435. doi: 10.1016/j.reprotox.2016.05.008

Figure 7.

Figure 7

Figure 7

Figure 7A: Western blot analysis of SIRT1 expression in whole kidney homogenates from 6 month old offspring previously exposed on GD1-PD21 to cigarette smoke. Kidney homogenates from CSE offspring at age 6 months exhibited a decrease of approximately 30% in expression of the metabolic regulatory protein SIRT1 when compared to Sham exposed (*p<0.05; n=3 per group). Long horizontal lines indicate mean signal intensity, with the standard deviation represented by the shorter horizontal bars.

Figure 7B: Western blot analysis of PEPCK expression in whole kidney homogenates from 6 month old offspring previously exposed GD1-PD21 to cigarette smoke. Kidney homogenates from CSE offspring at age 6 months exhibited an increase of approximately 70% in PEPCK expression in the fed state when compared to Sham exposed (*p<0.05; n=4 per group). Long horizontal lines indicate mean signal intensity, with the standard deviation represented by the shorter horizontal bars.