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. 2016 Oct 26;11(10):e0164976. doi: 10.1371/journal.pone.0164976

Fig 2. The miRNA signature of hypoxia in hMSCs.

Fig 2

Hierarchical clustering of hypoxia (a) induced and (b) down-regulated miRNAs (> 2 fold, p<0.05) in response to hypoxia (2% O2) in human bone marrow derived MSCs. Quantitative RT-PCR data of upregulated (c) mature miRNAs and (e) pre-miRNAs and downregulated (d) mature miRNAs and (f) pre-miRs of HRMs in human bone-marrow derived MSCs. The graphical data points in c, d, e and f represent mean ± S.D. of at least three independent experiments. (*P>0.01 and <0.05, **P<0.01).