. Author manuscript; available in PMC: 2017 Dec 15.

Published in final edited form as: Adv Drug Deliv Rev. 2016 Apr 26;107:206–212. doi: 10.1016/j.addr.2016.04.019

Table 2.

PLA Scaffolds for Nervous Tissue Engineering.

Scaffold type	Application	Reference
Multi-layer microbraided PLA suture conduit	Subcutaneous implantation in a rat	[50]
Multichannel nanofibrous PLLA conduit	In vitro cytocompatibility of neuroblasts and fibroblasts	[51]
Peptide-functionalized PLLA nanofibrous scaffold	In vitro differentiation of mouse embryonic stem cells	[55]
Drug-releasing coaxial electrospun PLLA/gelatin composite nanofibrous scaffold	In vitro neuronal stem cell differentiation and controlled release of neurogenic drugs	[56]
Growth-factor-releasing coaxial electrospun PLA/silk fibroin composite nanofibrous scaffold	In vitro release of nerve growth factor and PC12 neuronal stem cell differentiation and neurite extension	[24]
Aligned PLLA nanofibrous scaffold	In vitro culture of dorsal root ganglion cells and Schwann cells; neurite formation and extension	[57]