Figure 4. High doses of IgG2 antibodies reveal FcγRIV contribution to IgG2-PSA.
(A) PSA in indicated mice injected with various doses of IgG2a anti-TNP mAbs (n=2/group). (B-E) PSA in indicated mice (B&C: n=8/group; D&E: n≥3/group) injected with indicated doses of anti-TNP mAbs. Data are pooled from two independent experiments. Significant differences compared to the untreated WT group are indicated.
